Addressing variability in the acoustic startle reflex for accurate gap detection assessment
نویسندگان
چکیده
منابع مشابه
A New Statistical Approach for the Evaluation of Gap-prepulse Inhibition of the Acoustic Startle Reflex (GPIAS) for Tinnitus Assessment
Background: An increasingly used behavioral paradigm for the objective assessment of a possible tinnitus percept in animal models has been proposed by Turner and coworkers in 2006. It is based on gap-prepulse inhibition (PPI) of the acoustic startle reflex (ASR) and usually referred to as GPIAS. As it does not require conditioning it became the method of choice to study neuroplastic phenomena a...
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The progress in the field of tinnitus largely depends on the development of a reliable tinnitus animal model. Recently, a new method based on the acoustic startle reflex modification was introduced for tinnitus screening in laboratory animals. This method was enthusiastically adopted and now widely used by many scientists in the field due to its seeming simplicity and a number of advantages ove...
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Bacterial endotoxin (lipopolysaccharide; LPS) evokes in rodents an adaptive sickness behavior. It also produces changes in stress hormones secretion and activity of brain serotonergic and noradrenergic systems that have been implicated in stress responses, fear, and anxiety. Acoustic startle reflex (ASR) is regarded as a protective behavioral response that is enhanced in threatening situations ...
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This study analyzed the relationship of individual differences in personality with habituation in the acoustic startle response (ASR). Data from nine trials in ASR to white noise bursts and a personality questionnaire based on the alternative big five personality approach were modelled with a latent growth curve (LCM) including intercept and slope habituation growth factors. There was a negativ...
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This issue of Perspectives on Medical Education contains a thought-provoking article by Young, Cummings & StOnge, looking specifically at the stability of difficulty and discrimination indices when calculated for small samples of students. They concluded that difficulty and discrimination scores calculated based upon small samples are not stable across cohorts and therefore should be interprete...
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ژورنال
عنوان ژورنال: Hearing Research
سال: 2018
ISSN: 0378-5955
DOI: 10.1016/j.heares.2018.03.013